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For people in occupational settings that increase the risk of titanium dioxide exposure, taking protective measures is helpful. This may include wearing protective equipment, such as respirators, and using ventilation systems.


Other experts say there is simply no conclusive evidence at this point that titanium dioxide is damaging to humans after ingesting. Kaminski in particular said the research studies cite health hazards that were found by using high doses of the product, which you would not normally see in food.
Wegman’s puts titanium dioxide in its Original Macaroni and Cheese. Campbell’s Healthy Request Chunky Chicken Corn Chowder has it, as does Food Club’s Chunky New England Clam Chowder. Marzetti uses the color agent to brighten its Cream Cheese Fruit Dip. Dairy products usually don’t need titanium dioxide to look white, but Kroger has decided to add titanium dioxide to its Fat Free Half-and-Half. And titanium dioxide isn’t only in especially white or brightly colored foods: Little Debbie adds it to Fudge Rounds and many other products. According to the Food Scores database maintained by Environmental Working Group, more than 1,800 brand-name food products have titanium dioxide on their ingredients list. That said, it can still lurk as an unspecified “artificial color,” or labels might simply say “color added.”
Suppliers of Barium Sulphate
Lithopone B301, Lithopone B311 powder is also widely applied in paints and enamels
Risk managers at the European Commission and in EU Member States have been informed of EFSA’s conclusions and will consider appropriate action to take to ensure consumers’ protection.


So, what does it all mean for you, the consumer? Should you stop eating Skittles or begin checking foods for the presence of titanium dioxide? Here's a closer look.
Lithopone was discovered in the 1870s by DuPont. It was manufactured by Krebs Pigments and Chemical Company and other companies.[2] The material came in different seals, which varied in the content of zinc sulfide. Gold seal and Bronze seals contain 40-50% zinc sulfide, offering more hiding power and strength.[3] Although its popularity peaked around 1920, approximately 223,352 tons were produced in 1990. It is mainly used in paints, putty, and in plastics.[1]
In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.”


The produced barium sulfide enters the leacher, and the temperature is controlled above 65°C to obtain a barium sulfide content of 70%, and then enters the clarification barrel, add zinc sulfate for reaction after clarification, control the zinc sulfate content to be greater than 28%, pH=8~9, and obtain a mixture of barium sulfate and zinc sulfide with a density of 1.296~1.357 g/cm3.
Titanium dioxide (E 171) is authorised as a food additive in the EU according to Annex II of Regulation (EC) No 1333/2008.